Investigation into the prevalence of Helicobacter pylori infection in children in the age range of 2-16 years with chronic autoimmune (idiopathic) thrombocytopenic purpura referred to the hematological clinic between “2013-2015”

Introduction and purpose: Autoimmune (idiopathic) thrombocytopenic purpura ((ITP)) is the most common autoimmune blood disorder which leads to premature destruction of platelets by producing antibodies using phagocytic cells against antigens of platelets surface especially in the spleen. Recently, several studies have reported the high prevalence of H. pylori infection in adult patients with chronic autoimmune (idiopathic) thrombocytopenic purpura, but the studies performed in this area have been very limited in children. The purpose of this study is to investigate the prevalence of Helicobacter pylori infection in children with chronic idiopathic thrombocytopenic purpura. Material & Methods: This study is a control-case one and the population includes the children in the age range of 2-16 years referred to the hospital. The case sample includes 30 children in the age range of 2-16 years with chronic ITP and control samples includes 90 children in the age range of 2-16 years who are healthy in terms of ITP disease. A questionnaire and a stool sample is prepared for each sample. These samples are examined by the method of ELIZA kit for the presence or absence of antigen H.Pylori. Results: Of the total 30 children with chronic ITP who has referred to the hematology ward of the hospital, Hpylori + %16.7, we had Hpylori + %20 from a total of 90 controls (P=0.68). The average age of the case and control groups were 6.9 ± 2.8 and 6.9 ± 3 years, respectively; there is no a direct relationship between helicobacter pylori infection and sex, drinking water, but there is a statistically significant difference between platelet levels and the prevalence of H Pylori in the case group (p